Frequency Spectrum Analysis of Signals Used in Transcorneal Electrical Stimulation

Authors

DOI:

https://doi.org/10.21640/ns.v14i29.3136

Keywords:

genistein, maxi-channels, Fourier, frequency, bandwidth, spectrum, samples, biological behavior, electric fields, transcorneal stimulation, algorithms, cell behavior

Abstract

The contribution of this research work focuses on understanding the biological behavior of time-varying electric fields, specifically in the eyeball, by proposing sensitive frequency ranges, specifically for primary open-angle glaucoma POAG and RP retinitis pigmentosa. These ranges were obtained from the analysis of the frequency spectrum of the signals used by other authors in transcorneal electrical stimulation TES therapies. This analysis was performed using an algorithm proposed in this work. The frequency spectra of the signals used in the TES were also compared with the frequency response of the cellular behavior evoked by genestein drug, in order to compare the frequency characteristics of the signals applied in the TES and the biological response of the drug. which causes the same effect in POAG.

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Author Biographies

Jorge Santiago Amaya , SYS-DT S. A de C. V.

Research and Development Department. State of Mexico, Mexico

José Antonio Mendoza Hernández, Technological Institute of Higher Studies Chalco

Division of Electronic Engineering. State of Mexico, Mexico

Félix Gil Carrasco , A. I. P., Luis Sanchez Bulnes Hospital

Association to Prevent Blindness in Mexico (APEC). Mexico City

Jarumi Aguilar Guggembuhl, Technological Institute of Higher Studies Chalco

Division of Electronic Engineering. State of Mexico, Mexico

Claudio López García, Technological Institute of Higher Studies Chalco

Electromechanical Engineering Division. State of Mexico, Mexico

References

Cerro, D. S. (2005). Implicaciones funcionales de la señalización purinérgica en la red trabecular. (Tesis Doctoral). Universitat de Barcelona. Departament de Ciencies Fisiolegiques I. Barcelona.

Constane, H. (2008) Cellular and Molecular Neurophysiology, Third Edition. ISBN: 978-0-12-374127-1 2008

Robles-Camarillo, D., Niño-de-Rivera, L., Quiroz-Mercado, H., & Lopez-Miranda, M. J. (2008). Waveform generator system to transcorneal stimulation based on a digital adaptive model. 5th International Conference on Electrical Engineering, Computing Science and Automatic Control (pp. 207-211). 10.1109/ICEEE.2008.4723382

Stumpff, F., Que, Y., Boxberger, M., Strauss, O., & Wiederholt, M. (1999). Stimulation of Maxi-K Channels in Trabecular Meshwork by Tyrosine Kinase Inhibitors. Investigative ophthalmology & visual science, 40(7), 1404-17. http://dx.doi.org/10.17169/refubium-20182

Fujikado, T., Morimoto, T., Kanda, H. (2007). Evaluation of phosphenes elicited by extraocular stimulation in normals and by suprachoroidal-transretinal stimulation in patients with retinitis pigmentosa. Graefes Arch ClinExp Ophthalmol, 245, 1411–1419. 10.1007/s00417-007-0563-z

Gil-Carrasco, F., Ochoa-Contreras, D., Torres, M. A., Santiago-Amaya, J., Pérez-Tovar, F. W., González-Salinas, R., & Niño-de-Rivera, L. (2018). Transpalpebral Electrical Stimulation as a Novel Therapeutic Approach to Decrease Intraocular Pressure for Open-Angle Glaucoma: A Pilot Study. Journal of Ophtalmology 2018(7), 1-6. 10.1155/2018/2930519

Mason, K. A., Losos, J. B., & Singer, S. R. (2008). Biology. Mc Graw Hill.

Kato, M. (2006). Electromagnetics in Biology. Hokkaido University.

Toledo Castellano, M. Á., de la Garza Rosales, P., Garay Argueta, R. (2014). Procesamiento de señales analógicas y digitales. Ashok Ambardar.

Santiago J. A, Cristhian Romero, Santiago Guerrero, Francisco Trejo, Daniel Robles (2020). Bio-informatic model of tyrosine kinases inhibitors in trabecular meshwork cells. IOS Press. 10.3233/FAIA210034

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Published

2022-11-12

How to Cite

Santiago Amaya , J., Mendoza Hernández, J. A., Gil Carrasco , F. ., Aguilar Guggembuhl, J. ., & López García, C. . (2022). Frequency Spectrum Analysis of Signals Used in Transcorneal Electrical Stimulation. Nova Scientia, 14(29). https://doi.org/10.21640/ns.v14i29.3136

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Natural Sciences and Engineering

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